NovoMAC™ (Bone Marrow Aspirate Concentrate)
NovoMAC™ comes from your own bone marrow and contains a wealth of cells which can aid the body in its own recovery.
NovoMAC™ can be highly effective for bone, muscle, tendon, ligament and cartilage injuries. Bone marrow is an excellent source for the cells and growth factors that are responsible for the healing and tissue regeneration process.
How Much Bone Marrow is Needed?
Normally we draw 60 – 120 cc (2 – 4 ounces) of bone marrow.
Is Bone Marrow Safe?
Because NovoMAC™ is autologous, meaning it comes from the patient’s own body, the likelihood of any adverse side effects due to the NovoMAC™ itself is exceedingly low. We have never observed any adverse side effects in the thousands of patients he has treated.
In over 3000 orthopedic surgeries enhanced with NovoMAC™, an infection rate of 0% (none) has been observed. These results are simply astounding compared to the typical infection rate of 1-3%.
The Science Behind NovoMAC™
NovoMAC™ contains mesenchymal stem cells (MSC), CD34+ stem cells, growth factors and (mesenchymal) trophic factors (MTF).
MSC reduce inflammation, regulate the immune system and secrete factors that stimulate tissue regeneration. The better the blood supply, the faster surgical wounds and orthopedic injuries will heal and the more conducive the environment will be for MSC to flourish.
CD34+ stem cells are blood-forming cells. They induce blood vessels to grow (angiogenesis). CD34+ stem cells are the most angiogenic cells in the body.
Growth factors in NovoMAC™ are capable of stimulating cellular growth, proliferation, healing and differentiation (changing into another type of cell such as a blood vessel cell).
Mesenchymal Trophic Factors (MTF) are secreted by MSC. Most of the benefits commonly attributed to MSC (see above), are actually due to the trophic factors they secrete.